Major depression, 5HTTLPR genotype, suicide and antidepressant influences on thalamic volume
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چکیده
منابع مشابه
Major depression, 5HTTLPR genotype, suicide and antidepressant influences on thalamic volume.
BACKGROUND The 5HTTLPR genetic variant of the serotonin transporter gene (SERT or 5-HTT), which is comprised of a short (SERT-s) and a long (SERT-l) allele, is associated with major depressive disorder and post-traumatic brain disorder. AIMS The present study sought to determine whether the total thalamus and major subregions are altered in size in major depressive disorder and in relation to...
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Maintenance treatments in bipolar disorders and schizophrenia are securely established, and their discontinuation is associated with high but modifiable risk of early relapse. The benefits of long-term antidepressant treatment in major depression and the risks of discontinuing medication at various times after clinical recovery from acute depression are not as well defined. Computerized searchi...
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OBJECTIVE There is evidence from animal studies that fluoxetine may enhance the concentrations of neuroactive steroids. Therefore, the authors investigated whether clinically effective treatment with antidepressants may alter the concentrations of neuroactive steroids in patients suffering from a major depressive episode. METHOD In the first study, eight drug-naive outpatients with major depr...
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ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 2008
ISSN: 0007-1250,1472-1465
DOI: 10.1192/bjp.bp.107.039180